Have you heard of dental cavitations? These hidden problems in the jawbone can go undetected for years, yet they may have significant consequences for oral and overall health.
What are dental cavitations?
There is considerable confusion and misinformation surrounding dental cavitations, and some patients have been misled by incorrect diagnoses. The similarity between the terms dental cavitation and dental cavity (tooth decay) adds to the confusion.
A dental cavitation refers to an area of damage within the jawbone. Although “cavitation” is not strictly a formal medical term, it is used by clinicians to describe an empty or abnormal space within bone tissue. In clinical contexts this condition is often described as an area of infection, inflammation, or necrosis within the jawbone.
Unlike a dental cavity (dental caries), which is decay of tooth structure caused by acid-producing bacteria that destroy enamel, dentin, or the root surface, a cavitation involves the bone itself. If a true cavitation exists and is not treated appropriately, it can become a persistent source of infection and may contribute toxins that affect other parts of the body.
Because cavitation is not a universally recognized dental term, its diagnosis and management can be controversial. Some demineralized areas visible on imaging are not pathologic and do not require intervention. Treating those non-pathologic changes as cavitations can result in unnecessary surgery and expense. Distinguishing true cavitational disease from benign findings is essential.
Medical terminology
In medical literature, the condition most closely associated with dental cavitations is called cavitational osteonecrosis or ischemic osteonecrosis. These lesions may appear as hollowed spaces surrounded by dead bone or may be filled with inflammatory or infectious material.
Many of these lesions are painless and therefore remain undetected. When pain is present, the condition is sometimes labeled Neuralgia-Inducing Cavitational Osteonecrosis (NICO). Correct diagnosis is critical: areas of simple demineralization without pathology rarely need treatment, and an informed clinician will avoid unnecessary procedures when pathology is absent.
Diagnosis of cavitations
Diagnosing cavitational osteonecrosis can be challenging. Standard two-dimensional periapical or panoramic x-rays often fail to reveal these lesions because they flatten three-dimensional anatomy into a single plane and may obscure important detail.
For better visualization, a three-dimensional Cone Beam CT (CBCT) scan can reveal the extent and nature of a suspected lesion. Before ordering imaging, a clinician should thoroughly review the patient’s dental and medical history to identify potential causes or contributing factors and to avoid misinterpreting benign changes as disease.
Causes of dental cavitations
Cavitational lesions in the jawbone may arise from several types of injury or insult. Common contributing causes include:
- Trauma to the bone that compromises blood flow and leads to bone cell death.
- Incomplete healing after a tooth extraction, where retained infection or debris results in a chronic socket problem and eventual cavitation.
- Thermal injury to the bone from overheating during surgical procedures, which can cause localized bone necrosis.
- A tooth abscess that penetrates and becomes isolated within bone, creating a focal lesion.
- Persistent infection at the root of a tooth, such as a failing root canal, that extends into surrounding bone.
Linking dental cavitations to chronic disease
When bacteria and toxic products collect within a bone lesion, they can trigger local immune responses and generate biologically active chemicals. These substances may travel along nerve sheaths, through bone channels, via lymphatic routes, or into the bloodstream, potentially contributing to systemic inflammation.
Such inflammatory mediators and toxins can affect distant tissues and organs, potentially playing a role in chronic pain and systemic disease. Because symptoms may manifest far from the jaw, linking systemic complaints to a jawbone lesion can be difficult, which is why thorough clinical evaluation is important.
Published research
There are case reports and clinical studies addressing cavitational osteonecrosis and NICO. Published work includes case series and evaluations of patients with facial pain or implant-site lesions, which discuss diagnosis, progression, and treatment strategies. These publications provide clinical examples that support the existence of jawbone cavitational lesions and outline approaches used by clinicians to manage them.
While awareness of these lesions is limited among the general public and some dental practitioners, the available studies document human cases and their treatments, emphasizing the need for better recognition and research.
Treatment of dental cavitations
Treatment typically involves surgical access to the lesion, debridement, and removal of infected or necrotic tissue, with samples sent to pathology for analysis. Adjunctive methods such as laser decontamination or placement of biologically active graft materials may be used to promote healing of the bone space.
Comprehensive care should also support the patient’s overall immune function through nutrition and lifestyle measures. An integrative approach that includes an anti-inflammatory, nutrient-dense diet and attention to gut microbiome health can support recovery. In some cases, assessment for systemic toxicants, such as heavy metals, may be appropriate when they could impede healing.
Final thoughts
Although some clinicians remain skeptical about cavitational osteonecrosis, the clinical reports and case series that exist indicate that these lesions can occur and may have clinical significance. They often develop slowly after an initial bone insult and can remain hidden for some time.
Because symptoms and systemic effects can appear far from the jaw, increased documentation and research are needed to raise awareness among healthcare professionals so they can accurately diagnose and appropriately treat these conditions.
Dr. Al Danenberg is a nutritional periodontist offering online consultations. For appointments, contact his office directly.
References
- Glueck, C. J., McMahon, R. E., Bouquot, J. E., Khan, N. A., & Wang, P. (2010). T−786C polymorphism of the endothelial nitric oxide synthase gene and neuralgia-inducing cavitational osteonecrosis of the jaws. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 109(4), 548-553.
- Gandhi, Y. R., Pal, U. S., & Singh, N. (2012). Neuralgia-inducing cavitational osteonecrosis in a patient seeking dental implants. National Journal of Maxillofacial Surgery, 3(1), 84.
- Lechner, J., & von Baehr, V. (2015). Peripheral neuropathic facial/trigeminal pain and RANTES/CCL5 in jawbone cavitation. Evidence-Based Complementary and Alternative Medicine, 2015.
- Chen, Y. W., Simancas-Pallares, M., Marincola, M., & Chuang, S. K. (2017). Grafting and Dental Implantation in Patients With Jawbone Cavitation: Case Series and 3-Year Follow-Up. Implant Dentistry, 26(1), 158-164.